Health

Evidence-based guidelines for neurologic disorders.

Evidence-based review of stroke rehabilitation. From Parkwood Hospital London Ontario, Canada. Includes downloadable educational modules. 12th Edition, 2009.

Evidence-based review of 34 studies of both behavioral and developmental early intensive interventions for young children with autism spectrum disorders (ASDs). [2011]

Evidence-based systematic reviews of interventions in stroke rehabilitation for clinicians; those with stroke and their families. Includes ratings of interventions and assessments with levels of evidence rating. Canadian-based.

Updated evidence-based recommendations for the preventive treatment of migraine headache, from the American Academy of Neurology. [2013]

Evidence-based recommendations regarding management of tardive syndromes (TDS), including tardive dyskinesias (TDD); from the American Academy of Neurology. [2013]

Evidence-based review of the effects of nonpharmacologic and pharmacologic interventions on the functional abilities and behavior of patients with dementia, and how these can be implemented into clinical practice. [2012]

Examines for adult patients with HD requiring symptomatic chorea therapy what available pharmacologic and non-pharmacologic (CoQ10) agents effectively reduce chorea as measured by validated scales. From the American Academy of Neurology. [2012]

Review of best practices for primary and clinical care of ASD based on high-level evidence only (from randomized controlled trials (RCTs) or systematic reviews), covering its etiology, diagnosis and treatment. [2014]

Evidence-based guidance on the primary care of Alzheimer’s disease, including cognitive assessment, diagnosis and management. [2013]

Reviews the options for the acute and prophylactic management of migraine, both pharmacological, as well as invasive and noninvasive treatments, including neuromodulation. [2015]

Critical appraisal of the evidence on the definition, prevalence and stability, risk factors, screening, and management and intervention of mild cognitive impairment (MCI). [2016]

Review of strategies for switching antidepressants, including drug cessation versus gradual antidepressant withdrawal, and the issue of drug washout periods. [2016]

An evidence-based review of the modifiable risk factors of Alzheimer's Disease, especially vascular, and including dietary factors. [2009]

Outlines the current understanding of ASD and suggest best practices for primary care and specialized clinics based on evidence (when availablke) from randomized controlled trials (RCTs) or systematic reviews. [2014]

A review of recent research in the fields of neuroimaging, neuropsychology and genetics of ADHD, representing an update on recommendations from the British Association for Psychopharmacology (BAP) through 2014.

Evidence-based review of the landmark studies on the treatment and management of patients with life-threatening neurological illnesses, postoperative neurosurgical complications, and neurological manifestations of systemic disease. [2014]

Discusses the bioethics issues surrounding using evidence that some complementary and alternative treatments improve physiological abnormalities in autism, From the AMA Journal of Ethics. [2015]

Discusses the bioethics issues surrounding using evidence from complementary and alternative treatments for autism, advising only robust evidence-based interventions. From the AMA Journal of Ethics. [2015]

An evidence-based, mixed-methodologies, program of interdisciplinarity collaboration in dementia research from diagnosis through to end-of-life care. [2015]

An overview of current treatment options for the management of both core ASD symptoms and clinical features, including pharmacological, dietary, lifestyle, physical, behavorial, educational, psychosocial, and complementary and alternative medicine (CAM) interventions. [2015]

Up-to-date summary and critical analysis of both new and well-established ADHD interventions during 2014. [2015]

Evidence-based review that documents the lack of uniformity in clinical diagnosis of MCI, considered by some an intermediate state between normal ageing and dementia, as well for Alzheimer's disease and predementia, and argues for a uniform approach to MCI classification, and for any classification concept within the field of dementia. [2013]

Systematically reviews the evidence from 22 randomized controlled trials (RCTs) on the effects of physical exercise on cognition in older subjects with either MCI or dementia, with some positive effects on cognition found in studies on older subjects with MCI. [2014]

Reviews the association between the Mediterranean diet and cognitive impairment, finding higher adherence to the diet to be associated with a reduced risk of developing both MCI and Alzheimer's Disease, as well as a reduced risk of progressing from MCI to Alzheimer's. [2014]

Reviews in vitro, animal and epidemiological studies on the etiology of Alzheimer's Disease, highlighting evidence supportive of the link between toxic environmental exposures and the development of Alzheimer's pathology. [2015]

Systematic review investigating the impact of the urgent evaluation and initiation of treatment of patients with TIA on the risk of subsequent stroke and death. From the Ontario Health Technology Assessment Series. [2015]

An overview of the efficacy of disease-modifying therapies on conventional MS outcome measures, in order to prevent prevent the accumulation of irreversible neurological damage and reduce the risk of disease progression. [2015]

Review of high-level evidence from RCTs and meta-analyses of the effectiveness of acupuncture in the management of pain. [2015]

A review of the pathogenesis of cluster headaches and the evidence supporting the most promising treatment options. [2015]