Health

Discussion of the inadequacies of current schemes for the evaluation of evidence levels, along with a proposed scale of evidence levels for more appropriate to publications in pathology. [2011]

Analysis of requirements for clinical practice guidelines in order to facilitate implementation and strengthen confidence in recommendations about diagnostic tests. [2011]

ASCO Guideline on how to improve the accuracy of ER and PR testing in breast cancer and on the utility of these receptors as predictive markers. [2010]

Asks the question "Are pathologists, in fact, as evidence based as they believe?", showing large areas of both anatomic and clinical pathology where evidence-based methodologies have not been applied, and offering constructive suggestions for more systematic application.

Documents the lack of randomized clinical trials evaluating the prognosis of patients with thymomas and the effects of various treatment modalities, and calls for an international cooperative study and meta-analysis of thymomas. [2008]

Examines whether the practice of anatomic pathology fulfills the tenets of evidence-based medicine (EBM), arguing that anatomic pathology has in fact a unique place in the practice of EBM.

Review of the history and basic concepts of evidence-based medicine and evidence-based pathology, and how to perform and interpret systematic reviews, and integrate best evidence into guidelines. [2015]

Reviews history and basic concepts of evidence-based medicine and evidence-based pathology, how to perform and interpret systematic reviews, and how to integrate best evidence into guidelines. [2015]

A systematic review and meta-analysis of the prognostic importance of transcapsular invasion in thymoma stage I and II, finding it not a significant prognostic feature of any clinical value. [2008]