Science

Design and synthesis of new molecules with interesting properties.

Silicon chemistry.

Total synthesis.

Research on the total synthesis of bioactive natural products, heterocyclic compounds, organometallic compounds, macrocyclic ethers and lactones and porphyrazines. The team is additionally investigating the use of catalysis in organic synthesis and the development of combinatorial chemistry and parallel synthesis for pharmaceutical discovery and other applications.

Development of Clean Methods for Radical Chemistry. New Photochemical Methods for Natural Product Synthesis. Bioorganic Chemistry: Genes as 'Reagents' for Organic Synthesis.

Development and application of semiclassical and quantum dynamics methods for studies of excited state reaction dynamics and relaxation phenomena in polyatomic systems and sensitized semiconductor materials; ligand binding interactions and reactivity in biomolecules.

Total synthesis of biologically active natural products, the development of new synthetic methods, heterocyclic chemistry, bioorganic and medicinal chemistry, combinatorial chemistry, the study of DNA-agent interactions, and the chemistry of antitumor antibiotics.